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CAS 330784-47-9 Avanafil

A phosphodiesterase (PDE5) inhibitor, used to treat erectile dysfunction.

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Avanafil Description

Product Name:Avanafil
Synonyms:(S)-2-(2-Hydroxymethyl-1-pyrrolidinyl)-4-(3-chloro-4-methoxybenzylamino)-5-[(2-pyrimidinylmethyl)carbamoyl]pyrimidine; 4-[[(3-Chloro-4-methoxyphenyl)methyl] amino]-2-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide; TA 1790;
CAS NO:330784-47-9
Molecular Formula:C23H26ClN7O3
Molecular Weight:483.95
Melting Point:150-152°C
Density:1.372
Appearance:White to Off-White Solid
Storage:Sealed in dry, Store in the freezer, under -20°C
Solubility:DMSO (Slightly), Methanol (Slightly, Heated)

Why is this medication prescribed?

Avanafil is used to treat erectile dysfunction (ED: impotence; inability to get or keep an erection in men). Avanafil is in a class of medications called phosphodiesterase (PDE) inhibitors. It works by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erection. Avanafil does not cure erectile dysfunction or increase sexual desire. Avanafil does not prevent pregnancy or the spread of sexually transmitted diseases such as human immunodeficiency virus (HIV).

How should this medicine be used?

Avanafil comes as a tablet to take by mouth. For men taking the 100- mg or 200 mg doses, avanafil is usually taken with or without food as needed, about 15 minutes before sexual activity. For men taking the 50-mg dose, avanafil is usually taken with or without food as needed, about 30 minutes before sexual activity. Do not take avanafil more often than once in 24 hours. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take avanafil exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Your doctor will probably start you on an average dose of avanafil and may increase or decrease your dose depending on how you respond to the medication. Tell your doctor if avanafil is not working well or if you experience side effects.

Ask your pharmacist or doctor for a copy of the manufacturer’s information for the patient.

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