Yohimbine Hydrochloride Description
| Product Name: | Yohimbine Hydrochloride |
| Synonyms: | (16α,17α)-17-Hydroxy-yohimban-16-carboxylic Acid Methyl Ester Hydrochloride; Actibine; Antagonil; Aphrodyne; Dayto-Himbin; Erex; NIH 9689; NSC 19509; Thybine; Yocon; Yohimbe; Yohimbine Chloride; Yohimex; Yomax; |
| CAS NO: | 65-19-0 |
| EINECS: | 200-600-4 |
| Molecular Formula: | C21H27ClN2O3 |
| Molecular Weight: | 390.9 |
| Melting Point: | 288-290 °C (dec.)(lit.) |
| Appearance: | white to slightly yellow powder |
| Storage: | Keep in a dark place, Inert atmosphere, Room temperature |
| Solubility: | Soluble in dimethyl sulfoxide and methanol. |
Yohimbine, also known as quebrachine, is an indole alkaloid derived from the bark of the African tree Pausinystalia Yohimbe; also from the bark of the unrelated South American tree Aspidosperma quebracho-blanco. Yohimbine is an α2-adrenergic receptor antagonist and has been used in a variety of research projects. It is a veterinary drug used to reverse sedation in dogs and deer.
While yohimbine behaves as an aphrodisiac in some mammals, it does not do so in humans. It has been prescribed as a treatment for erectile dysfunction, although its reported clinical benefits were modest and it has largely been superseded by the PDE5 inhibitor class of drugs. Substances that have purported to be extracted from the Yohimbe tree have been marketed as dietary supplements for various purposes, but they contain highly variable amounts of yohimbine if any; no published scientific evidence supports their efficacy.
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